SEPN

$30.86

$

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes. Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.

Next Earnings

2026-02-25

Beta

3.852797

Average Volume

Market Cap

Last Dividend

CIK

0001984086

ISIN

US81734D1046

CUSIP

81734D104

CEO

Jeffrey T. Finer

Sector

Healthcare

Industry

Biotechnology

Full Time Employees

75

IPO Date

2024-10-25

Status

Active

Latest News

Title Headline Publisher Date
Septerna to Present at TD Cowen 46th Annual Health Care Conference SOUTH SAN FRANCISCO, Calif., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, announced that Jeffrey Finer, M.D. GlobeNewsWire 2026-02-24 08:00:00
Septerna (NASDAQ:SEPN) Stock Price Down 5.9% on Insider Selling Septerna, Inc. (NASDAQ: SEPN - Get Free Report)'s stock price traded down 5.9% during trading on Friday after an insider sold shares in the company. The company traded as low as $26.15 and last traded at $25.4950. 11,134 shares changed hands during trading, a decline of 96% from the average session volume of 291,271 shares. The Defense World 2026-02-22 04:36:58
Septerna Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, announced today that on February 6, 2026, the company's Board of Directors granted an inducement award to Mark A. Wilson, Septerna's Chief Legal Officer, consisting of a non-qualified stock option to purchase 165,000 shares of common stock under the Company's 2026 Inducement Plan. The award was granted as an inducement material to Mr. Wilson's employment in accordance with Nasdaq Listing Rule 5635(c)(4). GlobeNewsWire 2026-02-10 16:05:00
Septerna to Present Data from Phase 1 Clinical Trial of SEP-631 for the Treatment of Mast Cell-Driven Diseases at 2026 AAAAI Annual Meeting SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that the company will present data from its Phase 1 clinical trial of SEP-631 at the 2026 American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting, taking place February 27-March 2, 2026, in Philadelphia. GlobeNewsWire 2026-02-10 08:00:00
Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Officer SOUTH SAN FRANCISCO, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Mark A. GlobeNewsWire 2026-01-08 16:05:00
Septerna to Present at 44th Annual J.P. Morgan Healthcare Conference SOUTH SAN FRANCISCO, Calif., Dec. 17, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey Finer, M.D. GlobeNewsWire 2025-12-17 08:00:00
Septerna to Participate in 8th Annual Evercore Healthcare Conference SOUTH SAN FRANCISCO, Calif., Nov. 25, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that management will participate in a fireside chat at the 8th Annual Evercore Healthcare Conference on Tuesday, December 2, 2025, at 10:25 a.m. ET in Coral Gables, Florida. GlobeNewsWire 2025-11-25 08:00:00
Septerna's Novo Partnership Begins To Transform The Story Septerna, Inc. delivered a strong 3Q25, driven by partnership revenue from its transformative collaboration with Novo Nordisk. SEPN's Novo partnership brings $195M upfront, a potential $2.2B in milestones, and full R&D funding, reducing capital burden and boosting strategic position. The incretin-pathway GPCR program is closest to early milestones, with further upside tied to successful target validation and hit-to-lead advancements. Seeking Alpha 2025-11-25 02:58:26

SEC Filings

Type Filing Date Accepted Date Link
4 2026-02-20 2026-02-20 View Filing
SC 13G/A 2026-02-17 2026-02-17 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
4 2026-02-10 2026-02-10 View Filing
3 2026-01-15 2026-01-15 View Filing
8-K 2026-01-12 2026-01-12 View Filing
8-K 2026-01-08 2026-01-08 View Filing
4 2025-11-13 2025-11-13 View Filing
10-Q 2025-11-10 2025-11-10 View Filing
8-K 2025-11-10 2025-11-10 View Filing
4 2025-09-29 2025-09-29 View Filing
3 2025-09-29 2025-09-29 View Filing
8-K 2025-09-29 2025-09-29 View Filing
8-K 2025-09-03 2025-09-03 View Filing
8-K 2025-08-21 2025-08-21 View Filing
4 2025-08-19 2025-08-19 View Filing
4 2025-08-11 2025-08-11 View Filing
4 2025-08-11 2025-08-11 View Filing
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4 2025-08-11 2025-08-11 View Filing
4 2025-08-11 2025-08-11 View Filing
10-Q 2025-08-11 2025-08-11 View Filing
8-K 2025-08-11 2025-08-11 View Filing
8-K 2025-08-04 2025-08-04 View Filing
8-K 2025-07-02 2025-07-02 View Filing
4 2025-06-20 2025-06-20 View Filing
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4 2025-06-20 2025-06-20 View Filing
4 2025-06-20 2025-06-20 View Filing
8-K 2025-06-18 2025-06-18 View Filing
SC 13G/A 2025-06-10 2025-06-10 View Filing
SC 13G/A 2025-05-15 2025-05-15 View Filing
10-Q 2025-05-15 2025-05-15 View Filing
8-K 2025-05-15 2025-05-15 View Filing
SC 13G/A 2025-05-15 2025-05-15 View Filing
8-K 2025-05-14 2025-05-14 View Filing
SC 13G/A 2025-05-09 2025-05-09 View Filing
ARS 2025-04-29 2025-04-29 View Filing
DEFA14A 2025-04-29 2025-04-29 View Filing
DEF 14A 2025-04-29 2025-04-29 View Filing
4 2025-04-04 2025-04-04 View Filing
S-8 2025-03-27 2025-03-27 View Filing
10-K 2025-03-27 2025-03-27 View Filing
8-K 2025-03-27 2025-03-27 View Filing
4 2025-03-10 2025-03-10 View Filing
4 2025-03-06 2025-03-06 View Filing
8-K 2025-03-03 2025-03-03 View Filing
4 2025-02-27 2025-02-27 View Filing
4 2025-02-27 2025-02-27 View Filing
4 2025-02-26 2025-02-26 View Filing
4 2025-02-24 2025-02-24 View Filing
4 2025-02-21 2025-02-21 View Filing
8-K 2025-02-18 2025-02-18 View Filing
SC 13G 2025-02-14 2025-02-14 View Filing
SC 13G 2025-02-13 2025-02-13 View Filing
4 2025-02-07 2025-02-07 View Filing
8-K 2025-01-13 2025-01-13 View Filing
3 2025-01-07 2025-01-07 View Filing
8-K 2025-01-06 2025-01-06 View Filing
10-Q 2024-11-20 2024-11-20 View Filing
8-K 2024-11-20 2024-11-20 View Filing
SC 13D 2024-11-04 2024-11-04 View Filing
SC 13G 2024-11-04 2024-11-04 View Filing
SC 13G 2024-11-01 2024-11-01 View Filing
4 2024-10-30 2024-10-30 View Filing
4 2024-10-28 2024-10-28 View Filing
8-K 2024-10-28 2024-10-28 View Filing
S-8 2024-10-25 2024-10-25 View Filing
424B4 2024-10-25 2024-10-25 View Filing
EFFECT 2024-10-25 2024-10-25 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
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3 2024-10-24 2024-10-24 View Filing
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3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
3 2024-10-24 2024-10-24 View Filing
S-1MEF 2024-10-24 2024-10-24 View Filing
CERT 2024-10-24 2024-10-24 View Filing
S-1/A 2024-10-24 2024-10-24 View Filing
8-A12B 2024-10-22 2024-10-22 View Filing

Algorithm Performance

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Algorithm Profit/Loss Profit Factor # Trades Sharpe Sortino Efficiency
Larry Williams PercentR Strategy 18.98% 0.83 14 0.65 0.61 22.76
Adaptive Wave 14.77% 1.98 3 0.74 0.81 18.56
Market Cycle 14.43% 1 1 0.6 0.56 18.22
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