SEPN
$30.86
$
Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes. Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.
Next Earnings
2026-02-25
Beta
3.852797
Average Volume
Market Cap
Last Dividend
CIK
0001984086
ISIN
US81734D1046
CUSIP
81734D104
CEO
Jeffrey T. Finer
Sector
Healthcare
Industry
Biotechnology
Full Time Employees
75
IPO Date
2024-10-25
Status
Active
Latest News
| Title | Headline | Publisher | Date |
|---|---|---|---|
| Septerna to Present at TD Cowen 46th Annual Health Care Conference | SOUTH SAN FRANCISCO, Calif., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, announced that Jeffrey Finer, M.D. | GlobeNewsWire | 2026-02-24 08:00:00 |
| Septerna (NASDAQ:SEPN) Stock Price Down 5.9% on Insider Selling | Septerna, Inc. (NASDAQ: SEPN - Get Free Report)'s stock price traded down 5.9% during trading on Friday after an insider sold shares in the company. The company traded as low as $26.15 and last traded at $25.4950. 11,134 shares changed hands during trading, a decline of 96% from the average session volume of 291,271 shares. The | Defense World | 2026-02-22 04:36:58 |
| Septerna Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) | SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, announced today that on February 6, 2026, the company's Board of Directors granted an inducement award to Mark A. Wilson, Septerna's Chief Legal Officer, consisting of a non-qualified stock option to purchase 165,000 shares of common stock under the Company's 2026 Inducement Plan. The award was granted as an inducement material to Mr. Wilson's employment in accordance with Nasdaq Listing Rule 5635(c)(4). | GlobeNewsWire | 2026-02-10 16:05:00 |
| Septerna to Present Data from Phase 1 Clinical Trial of SEP-631 for the Treatment of Mast Cell-Driven Diseases at 2026 AAAAI Annual Meeting | SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that the company will present data from its Phase 1 clinical trial of SEP-631 at the 2026 American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting, taking place February 27-March 2, 2026, in Philadelphia. | GlobeNewsWire | 2026-02-10 08:00:00 |
| Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Officer | SOUTH SAN FRANCISCO, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Mark A. | GlobeNewsWire | 2026-01-08 16:05:00 |
| Septerna to Present at 44th Annual J.P. Morgan Healthcare Conference | SOUTH SAN FRANCISCO, Calif., Dec. 17, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey Finer, M.D. | GlobeNewsWire | 2025-12-17 08:00:00 |
| Septerna to Participate in 8th Annual Evercore Healthcare Conference | SOUTH SAN FRANCISCO, Calif., Nov. 25, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that management will participate in a fireside chat at the 8th Annual Evercore Healthcare Conference on Tuesday, December 2, 2025, at 10:25 a.m. ET in Coral Gables, Florida. | GlobeNewsWire | 2025-11-25 08:00:00 |
| Septerna's Novo Partnership Begins To Transform The Story | Septerna, Inc. delivered a strong 3Q25, driven by partnership revenue from its transformative collaboration with Novo Nordisk. SEPN's Novo partnership brings $195M upfront, a potential $2.2B in milestones, and full R&D funding, reducing capital burden and boosting strategic position. The incretin-pathway GPCR program is closest to early milestones, with further upside tied to successful target validation and hit-to-lead advancements. | Seeking Alpha | 2025-11-25 02:58:26 |
SEC Filings
| Type | Filing Date | Accepted Date | Link |
|---|---|---|---|
| 4 | 2026-02-20 | 2026-02-20 | View Filing |
| SC 13G/A | 2026-02-17 | 2026-02-17 | View Filing |
| 4 | 2026-02-10 | 2026-02-10 | View Filing |
| 4 | 2026-02-10 | 2026-02-10 | View Filing |
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| 4 | 2026-02-10 | 2026-02-10 | View Filing |
| 4 | 2026-02-10 | 2026-02-10 | View Filing |
| 3 | 2026-01-15 | 2026-01-15 | View Filing |
| 8-K | 2026-01-12 | 2026-01-12 | View Filing |
| 8-K | 2026-01-08 | 2026-01-08 | View Filing |
| 4 | 2025-11-13 | 2025-11-13 | View Filing |
| 10-Q | 2025-11-10 | 2025-11-10 | View Filing |
| 8-K | 2025-11-10 | 2025-11-10 | View Filing |
| 4 | 2025-09-29 | 2025-09-29 | View Filing |
| 3 | 2025-09-29 | 2025-09-29 | View Filing |
| 8-K | 2025-09-29 | 2025-09-29 | View Filing |
| 8-K | 2025-09-03 | 2025-09-03 | View Filing |
| 8-K | 2025-08-21 | 2025-08-21 | View Filing |
| 4 | 2025-08-19 | 2025-08-19 | View Filing |
| 4 | 2025-08-11 | 2025-08-11 | View Filing |
| 4 | 2025-08-11 | 2025-08-11 | View Filing |
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| 4 | 2025-08-11 | 2025-08-11 | View Filing |
| 10-Q | 2025-08-11 | 2025-08-11 | View Filing |
| 8-K | 2025-08-11 | 2025-08-11 | View Filing |
| 8-K | 2025-08-04 | 2025-08-04 | View Filing |
| 8-K | 2025-07-02 | 2025-07-02 | View Filing |
| 4 | 2025-06-20 | 2025-06-20 | View Filing |
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| 4 | 2025-06-20 | 2025-06-20 | View Filing |
| 4 | 2025-06-20 | 2025-06-20 | View Filing |
| 8-K | 2025-06-18 | 2025-06-18 | View Filing |
| SC 13G/A | 2025-06-10 | 2025-06-10 | View Filing |
| SC 13G/A | 2025-05-15 | 2025-05-15 | View Filing |
| 10-Q | 2025-05-15 | 2025-05-15 | View Filing |
| 8-K | 2025-05-15 | 2025-05-15 | View Filing |
| SC 13G/A | 2025-05-15 | 2025-05-15 | View Filing |
| 8-K | 2025-05-14 | 2025-05-14 | View Filing |
| SC 13G/A | 2025-05-09 | 2025-05-09 | View Filing |
| ARS | 2025-04-29 | 2025-04-29 | View Filing |
| DEFA14A | 2025-04-29 | 2025-04-29 | View Filing |
| DEF 14A | 2025-04-29 | 2025-04-29 | View Filing |
| 4 | 2025-04-04 | 2025-04-04 | View Filing |
| S-8 | 2025-03-27 | 2025-03-27 | View Filing |
| 10-K | 2025-03-27 | 2025-03-27 | View Filing |
| 8-K | 2025-03-27 | 2025-03-27 | View Filing |
| 4 | 2025-03-10 | 2025-03-10 | View Filing |
| 4 | 2025-03-06 | 2025-03-06 | View Filing |
| 8-K | 2025-03-03 | 2025-03-03 | View Filing |
| 4 | 2025-02-27 | 2025-02-27 | View Filing |
| 4 | 2025-02-27 | 2025-02-27 | View Filing |
| 4 | 2025-02-26 | 2025-02-26 | View Filing |
| 4 | 2025-02-24 | 2025-02-24 | View Filing |
| 4 | 2025-02-21 | 2025-02-21 | View Filing |
| 8-K | 2025-02-18 | 2025-02-18 | View Filing |
| SC 13G | 2025-02-14 | 2025-02-14 | View Filing |
| SC 13G | 2025-02-13 | 2025-02-13 | View Filing |
| 4 | 2025-02-07 | 2025-02-07 | View Filing |
| 8-K | 2025-01-13 | 2025-01-13 | View Filing |
| 3 | 2025-01-07 | 2025-01-07 | View Filing |
| 8-K | 2025-01-06 | 2025-01-06 | View Filing |
| 10-Q | 2024-11-20 | 2024-11-20 | View Filing |
| 8-K | 2024-11-20 | 2024-11-20 | View Filing |
| SC 13D | 2024-11-04 | 2024-11-04 | View Filing |
| SC 13G | 2024-11-04 | 2024-11-04 | View Filing |
| SC 13G | 2024-11-01 | 2024-11-01 | View Filing |
| 4 | 2024-10-30 | 2024-10-30 | View Filing |
| 4 | 2024-10-28 | 2024-10-28 | View Filing |
| 8-K | 2024-10-28 | 2024-10-28 | View Filing |
| S-8 | 2024-10-25 | 2024-10-25 | View Filing |
| 424B4 | 2024-10-25 | 2024-10-25 | View Filing |
| EFFECT | 2024-10-25 | 2024-10-25 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| 3 | 2024-10-24 | 2024-10-24 | View Filing |
| S-1MEF | 2024-10-24 | 2024-10-24 | View Filing |
| CERT | 2024-10-24 | 2024-10-24 | View Filing |
| S-1/A | 2024-10-24 | 2024-10-24 | View Filing |
| 8-A12B | 2024-10-22 | 2024-10-22 | View Filing |
Algorithm Performance
| Algorithm | Profit/Loss | Profit Factor | # Trades | Sharpe | Sortino | Efficiency |
|---|---|---|---|---|---|---|
| Larry Williams PercentR Strategy | 18.98% | 0.83 | 14 | 0.65 | 0.61 | 22.76 |
| Adaptive Wave | 14.77% | 1.98 | 3 | 0.74 | 0.81 | 18.56 |
| Market Cycle | 14.43% | 1 | 1 | 0.6 | 0.56 | 18.22 |
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