PYXS

$1.48

$

Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

Next Earnings

2026-02-25

Beta

1.462

Average Volume

Market Cap

Last Dividend

CIK

0001782223

ISIN

US7473241013

CUSIP

747324101

CEO

Thomas Civik

Sector

Healthcare

Industry

Biotechnology

Full Time Employees

44

IPO Date

2021-10-08

Status

Active

Latest News

Title Headline Publisher Date
Pyxis Oncology, Inc. (NASDAQ:PYXS) Given Average Rating of “Moderate Buy” by Brokerages Shares of Pyxis Oncology, Inc. (NASDAQ: PYXS - Get Free Report) have earned an average recommendation of "Moderate Buy" from the seven research firms that are covering the stock, MarketBeat reports. One analyst has rated the stock with a sell rating, one has issued a hold rating and five have assigned a buy rating to the Defense World 2026-02-21 04:10:48
Pyxis Oncology Announces Interim CEO Appointment and Leadership Transition to Support Strategic Focus and Program Continuity BOSTON, Feb. 03, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced a leadership transition to continue execution and advancement of the Company's strategic and clinical goals. GlobeNewsWire 2026-02-03 06:45:00
Pyxis Oncology, Inc. (NASDAQ:PYXS) Short Interest Update Pyxis Oncology, Inc. (NASDAQ: PYXS - Get Free Report) was the target of a large growth in short interest in January. As of January 15th, there was short interest totaling 2,307,831 shares, a growth of 33.1% from the December 31st total of 1,733,403 shares. Currently, 4.1% of the company's stock are short sold. Based on an Defense World 2026-02-02 01:43:13
Pyxis Oncology, Inc. (NASDAQ:PYXS) Given Consensus Recommendation of “Moderate Buy” by Brokerages Pyxis Oncology, Inc. (NASDAQ: PYXS - Get Free Report) has been assigned a consensus recommendation of "Moderate Buy" from the seven brokerages that are covering the firm, Marketbeat.com reports. One research analyst has rated the stock with a sell recommendation, one has issued a hold recommendation and five have given a buy recommendation to the company. Defense World 2026-01-02 03:28:47
Analysts Sound Alarm On Pyxis Oncology's Tiny Trial Pyxis Oncology Inc. (NASDAQ: PYXS) on Thursday released preliminary data from its ongoing Phase 1 studies of micvotabart pelidotin (MICVO) for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). Benzinga 2025-12-19 09:07:43
Pyxis Oncology, Inc. (PYXS) Discusses Preliminary Phase 1 Data for MICVO in Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma Transcript Pyxis Oncology, Inc. (PYXS) Discusses Preliminary Phase 1 Data for MICVO in Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma Transcript Seeking Alpha 2025-12-18 14:57:37
Pyxis Oncology Announces Positive Preliminary Phase 1 Data for Micvotabart Pelidotin (MICVO) in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma BOSTON, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced positive preliminary data from its ongoing Phase 1 clinical studies evaluating micvotabart pelidotin (MICVO), a first-in-concept antibody-drug conjugate (ADC) targeting extradomain-B of fibronectin (EDB+FN), a non-cellular structural component of the tumor extracellular matrix (ECM), in patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). The update includes preliminary data from both the Phase 1 monotherapy study in 2L+ R/M HNSCC and the Phase 1/2 study evaluating MICVO in combination with Merck's (known as MSD outside of the US and Canada) anti-PD-1 therapy, pembrolizumab, in 1L/2L+ R/M HNSCC. GlobeNewsWire 2025-12-18 07:00:00

SEC Filings

Type Filing Date Accepted Date Link
SC 13G/A 2026-02-09 2026-02-09 View Filing
8-K 2026-02-06 2026-02-06 View Filing
4 2026-02-05 2026-02-05 View Filing
8-K 2025-12-18 2025-12-18 View Filing
EFFECT 2025-12-09 2025-12-10 View Filing
S-3 2025-11-26 2025-11-26 View Filing
10-Q 2025-11-03 2025-11-03 View Filing
8-K 2025-11-03 2025-11-03 View Filing
SC 13G/A 2025-10-14 2025-10-14 View Filing
SC 13G 2025-09-23 2025-09-23 View Filing
10-Q 2025-08-14 2025-08-14 View Filing
8-K 2025-08-14 2025-08-14 View Filing
8-K 2025-08-04 2025-08-04 View Filing
SC 13G/A 2025-07-17 2025-07-17 View Filing
8-K 2025-07-03 2025-07-02 View Filing
SC 13G 2025-07-01 2025-07-01 View Filing
8-K 2025-06-18 2025-06-18 View Filing
10-Q 2025-05-15 2025-05-15 View Filing
8-K 2025-05-15 2025-05-15 View Filing
SC 13G/A 2025-05-06 2025-05-06 View Filing
DEFA14A 2025-04-29 2025-04-29 View Filing
DEF 14A 2025-04-29 2025-04-29 View Filing
SC 13D/A 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
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4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
4 2025-04-02 2025-04-02 View Filing
8-K 2025-03-24 2025-03-24 View Filing
S-8 2025-03-18 2025-03-18 View Filing
10-K 2025-03-18 2025-03-18 View Filing
8-K 2025-03-18 2025-03-18 View Filing
8-K 2025-02-26 2025-02-26 View Filing
SC 13G/A 2025-02-14 2025-02-14 View Filing
SC 13G/A 2025-02-14 2025-02-14 View Filing
SC 13G 2025-02-04 2025-02-04 View Filing
8-K 2025-02-04 2025-02-04 View Filing
SC 13D/A 2024-12-23 2024-12-23 View Filing
4 2024-12-23 2024-12-23 View Filing
4 2024-12-23 2024-12-23 View Filing
4 2024-12-23 2024-12-23 View Filing
8-K 2024-12-19 2024-12-19 View Filing
SC 13G 2024-12-16 2024-12-16 View Filing
4 2024-11-27 2024-11-27 View Filing
8-K 2024-11-20 2024-11-20 View Filing
S-8 2024-11-12 2024-11-12 View Filing
SC 13G/A 2024-11-12 2024-11-12 View Filing
10-Q 2024-11-12 2024-11-12 View Filing
SC 13G/A 2024-11-06 2024-11-06 View Filing
8-K 2024-10-23 2024-10-23 View Filing
DEF 14A 2024-09-25 2024-09-25 View Filing
PRE 14A 2024-09-13 2024-09-13 View Filing
10-Q 2024-08-14 2024-08-14 View Filing
8-K 2024-08-14 2024-08-14 View Filing
8-K 2024-06-12 2024-06-12 View Filing
4 2024-06-10 2024-06-10 View Filing
3 2024-06-10 2024-06-10 View Filing
8-K 2024-06-10 2024-06-10 View Filing
4 2024-06-07 2024-06-07 View Filing
10-Q 2024-05-14 2024-05-14 View Filing
8-K 2024-05-14 2024-05-14 View Filing
ARS 2024-04-26 2024-04-26 View Filing
DEFA14A 2024-04-26 2024-04-26 View Filing
DEF 14A 2024-04-26 2024-04-26 View Filing
EFFECT 2024-04-04 2024-04-04 View Filing
424B2 2024-04-04 2024-04-03 View Filing
SC 13D/A 2024-04-03 2024-04-03 View Filing
4 2024-03-28 2024-03-28 View Filing
4 2024-03-28 2024-03-28 View Filing
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4 2024-03-28 2024-03-28 View Filing
4 2024-03-28 2024-03-28 View Filing
4 2024-03-28 2024-03-28 View Filing
4 2024-03-28 2024-03-28 View Filing
S-3 2024-03-27 2024-03-27 View Filing
8-K 2024-03-27 2024-03-27 View Filing
8-K 2024-03-27 2024-03-27 View Filing
S-8 2024-03-22 2024-03-21 View Filing
10-K 2024-03-21 2024-03-21 View Filing
8-K 2024-03-21 2024-03-21 View Filing
4 2024-03-13 2024-03-13 View Filing
3 2024-03-13 2024-03-13 View Filing
8-K 2024-03-13 2024-03-13 View Filing
SC 13G 2024-03-08 2024-03-08 View Filing
8-K 2024-02-28 2024-02-28 View Filing

Algorithm Performance

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Algorithm Profit/Loss Profit Factor # Trades Sharpe Sortino Efficiency
RSI Overbought Strategy 38.88% 1.18 14 0.82 0.68 72.3
Heikin Ashi Strategy 36.34% 0.91 7 0.66 0.75 69.76
Williams PercentR Strategy 30.26% 0.98 26 0.6 0.31 63.68
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